分泌型卷曲相关蛋白5(SFRP5)重组蛋白

Recombinant Secreted Frizzled Related Protein 5 (SFRP5)

SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b

  • 编号RPC842Ra01
  • 物种Rattus norvegicus (Rat,大鼠) 相同的名称,不同的物种。
  • 所有
  • 小鼠
  • 大鼠
  • 豚鼠
  • 家兔
  • 猕猴
  • 山羊
  • 绵羊
  • 其他物种
  • 多物种
  • 泛物种
  • 来源原核表达
  • 宿主E.coli
  • 内毒素水平<1.0EU/µg(LAL法测定)
  • 亚细胞定位分泌
  • 预测分子量14.8kDa
  • 实际分子量15kDa(差异分析请参阅说明书)
  • 片段与标签Ser45~Val162 with N-terminal His Tag
  • 缓冲液成份20mM Tris, 150mM NaCl缓冲液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
  • 性状冻干粉
  • 纯度> 90%
  • 等电点6.6
  • 应用 Positive Control; Immunogen; SDS-PAGE; WB.
    如果需要有生物活性的蛋白,请参见活性蛋白。
  • 下载 英文说明书   中文说明书
  • 规格 10µg50µg 200µg 1mg 5mg
  • 价格 ¥ 1008 ¥ 2520 ¥ 5040 ¥ 15120 ¥ 37800
  • 欲了解实际交易价格和更多情况,请与当地经销商联系!
  • 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 产品包装(模拟)
  • 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 产品包装(模拟)
  • RPC842Ra01.jpg SDS-PAGE图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证
  • 序列

    用法

    Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

    储存

    避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。

    稳定性

    热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

    赠品

    聚丙烯酰胺凝胶电泳(PAGE)实验服务

    增值服务

    去内毒素河北快三走势图表
    BCA蛋白定量检测河北快三走势图表
    蛋白标记定制服务
    蛋白分子量MARKER
    重组蛋白定制服务
    单克隆抗体定制服务
    多克隆抗体定制服务
    蛋白活性测定实验服务
    免疫沉淀(IP)实验服务
    缓冲液
    内毒素去除河北快三走势图表Ⅱ
    实时荧光定量PCR实验服务

    相关产品

    编号
    适用物种:Rattus norvegicus (Rat,大鼠)
    应用(仅供研究使用,不用于临床诊断!)
    RPC842Ra01
    分泌型卷曲相关蛋白5(SFRP5)重组蛋白
    Positive Control; Immunogen; SDS-PAGE; WB.
    PAC842Ra01
    分泌型卷曲相关蛋白5(SFRP5)多克隆抗体
    WB; IHC; ICC; IP.
    LAC842Ra71
    分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记)
    WB; IHC; ICC.
    MAC842Ra21
    分泌型卷曲相关蛋白5(SFRP5)单克隆抗体
    WB; IHC; ICC; IP.
    SEC842Ra
    分泌型卷曲相关蛋白5(SFRP5)检测河北快三走势图表(酶联免疫吸附试验法)
    Enzyme-linked immunosorbent assay for Antigen Detection.

    参考文献

    杂志
    参考文献
    Diabetes Research and Clinical Practice
    Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance [PubMed: 23290274]
    European Journal of Clinical Investigation
    Sfrp5 correlates with insulin resistance and oxidative stress [PubMed: 23398169]
    Pediatric Research
    Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children [Pubmed: 24603290]
    Clin Endocrinol (Oxf).
    SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children [Pubmed: 24330025]
    The Journal of Clinical Endocrinology & Metabolism
    Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans [Pubmed: 23185036]
    Atherosclerosis
    Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease [Pubmed: 24530778]
    PLoS One.
    Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation [Pubmed:Pmc4072672]
    J Clin Endocrinol Metab.
    Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation [Pubmed:24840810]
    Oncology Letters
    Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma [Pubmed:25120720]
    Diabetes Metab Res Rev.
    Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls [Pubmed:25139699]
    Clinical &amp; Experimental Immunology
    The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis [Pubmed:25382802]
    Diabetes Metab Res Rev
    Circulating SFRP5 levels are elevated in drug-na [PubMed: 25139699]
    J Matern Fetal Neonatal Med
    Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels [PubMed: 26100762]
    Eur J Clin Invest
    Sfrp5 associates with beta-cell function in humans [Pubmed:27019073]
    Osteoporosis International
    Bone marrow sFRP5 level is negatively associated with bone formation markers [pubmed:27986984]
    Diabetes/Metabolism Research and Reviews
    Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults [pubmed:28303637]
    Cardiovascular Diabetology
    Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study [pubmed:28851362]
    Arteriosclerosis, Thrombosis, and Vascular Biology 
    Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With … [Pubmed:29674475]
    Obesity
    Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans [Pubmed:29427376]
    J Bas Res Med Sci
    Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats [article-1-352-en.pdf]
    Molecular Biology Reports
    The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome [Pubmed: 30194556]
    Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling []
    British Journal Of Nutrition
    A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile [Pubmed: 30375290]
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